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Fig. 3 | Molecular Medicine

Fig. 3

From: Lansoprazole-induced osteoporosis via the IP3R- and SOCE-mediated calcium signaling pathways

Fig. 3

Cell proliferation, viability and apoptosis were examined by CCK-8 assays, EdU assays and flow cytometry. A MC3T3-E1 cells were treated with increasing concentrations of LPZ, and the EdU assay showed a reduction in proliferation. B Apoptosis in osteoblasts pretreated with LPZ (0, 5, 10, 20, 50 µM) for 24 h. C Number of cells, as determined by the EdU assays. D Quantitative analysis of apoptotic rates. E The viability of MC3T3-E1 cells after LPZ treatment. *P < 0.05, **P < 0.01 (n = 3)

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