Fig. 1
From: LncRNA LINC00461 exacerbates myocardial ischemia–reperfusion injury via microRNA-185-3p/Myd88
LINC00461 binds to miR-185-3p; LINC00461 is up-regulated while miR-185-3p is down-regulated in I/R mice. A Dual luciferase reporter gene assay verified the regulatory relationship between LINC00461 and miR-185-3p. B The relationship between LINC00461 and miR-185-3p in myocardial tissue by RNA-pull down assay. C Expression of LINC00461 and miR-185-3p in myocardial tissue of mice in each group. a P < 0.05 vs. the sham group. b P < 0.05 vs. the si-NC group. c P < 0.05 vs. the mimic-NC group. d P < 0.05 vs. the OE-LINC00461 + mimic NC group