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Fig. 5 | Molecular Medicine

Fig. 5

From: Effectiveness of high cardiorespiratory fitness in cardiometabolic protection in prediabetic rats

Fig. 5

Cardiac mitochondrial ROS production (a), Cardiac mitochondrial membrane depolarization (b), Cardiac mitochondrial swelling indicated by the normalized absorbance at λ 540 nm (c), Cardiac respiratory control ratio (d), Cardiac OXPHOS protein expression (e). VDAC was used as a housekeeping protein. n = 5–6 per group. Data are reported as mean ± SEM. *p < 0.05 when compared to ND, †p < 0.05 when compared to PDM, ‡p < 0.05 when compared to PDMCR-SM, §p < 0.05 when compared to PDMCR-L, ‖p < 0.05 when compared to PDMEX-SM. ND: Normal diet; PDM: Prediabetes with no intervention; PDMCR-SM: Prediabetes with short-term caloric restriction followed by weight maintenance; PDMCR-L: Prediabetes with long-term caloric restriction; PDMEX-SM: Prediabetes with short-term exercise followed by weight maintenance; PDMEX-L: Prediabetes with long-term exercise

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