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Table 1 Insulin resistance profile and lipid profile in the blood

From: Effectiveness of high cardiorespiratory fitness in cardiometabolic protection in prediabetic rats

Parameters

Week 12

Week 28

ND

(n = 6)

PDM

(n = 30)

ND

(n = 6)

PDM

(n = 6)

PDMCR-SM

(n = 6)

PDMCR-L

(n = 6)

PDMEX-SM

(n = 6)

PDMEX-L

(n = 6)

Fasting glucose (mg/dL)

107.90 ± 6.35

183.82 ± 5.64*

183.45 ± 7.82

228.86 ± 15.70*

164.88 ± 12.56†

143.54 ± 6.44*†

183.15 ± 19.67†§

186.89 ± 4.32†§

Fasting insulin (mU/mL)

4.55 ± 0.67

7.25 ± 0.64*

5.55 ± 0.84

9.60 ± 1.29*

5.32 ± 0.57†

5.45 ± 1.02†

5.81 ± 1.55†

6.02 ± 1.08†

HOMA-IR

1.24 ± 0.23

3.09 ± 0.32*

3.38 ± 0.39

5.68 ± 0.68*

2.51 ± 0.23†

1.59 ± 0.21*†

3.41 ± 0.90†§

3.39 ± 0.67†§

Triglyceride (mg/dL)

56.99 ± 8.72

84.37 ± 5.50*

121.11 ± 11.21

199.58 ± 19.92*

123.65 ± 12.68†

78.21 ± 5.12*†‡

123.50 ± 9.53†§

122.92 ± 12.69†§

Total cholesterol (mg/dL)

74.15 ± 5.52

98.78 ± 4.65*

98.52 ± 8.52

132.4 ± 9.03*

99.43 ± 806†

98.00 ± 4.80†

96.61 ± 8.95†

98.06 ± 8.74†

HDL (mg/dL)

29.64 ± 1.29

22.40 ± 0.98*

33.41 ± 1.40

23.98 ± 2.27*

34.57 ± 1.97†

34.07 ± 2.64†

33.90 ± 2.60†

34.12 ± 2.65†

Calculated LDL (mg/dL)

29.68 ± 3.58

53.90 ± 3.56*

46.49 ± 8.89

73.90 ± 3.53*

46.58 ± 7.30†

45.69 ± 1.36†

43.03 ± 7.89†

41.45 ± 9.03†

  1. Data are reported as mean ± SEM
  2. *p < 0.05 when compared to ND, †p < 0.05 when compared to PDM, ‡p < 0.05 when compared to PDMCR-SM, §p < 0.05 when compared to PDMCR-L, ‖p < 0.05 when compared to PDMEX-SM
  3. ND: Normal diet; PDM: Prediabetes with no intervention; PDMCR-SM: Prediabetes with short-term caloric restriction followed by weight maintenance; PDMCR-L: Prediabetes with long-term caloric restriction; PDMEX-SM: Prediabetes with short-term exercise followed by weight maintenance; PDMEX-L: Prediabetes with long-term exercise