Fig. 2

Proteins altered in asymptomatic patients’ serum and functional network. A Hierarchical clustering comparing the proteins patterns of the three groups analyzed. B Graphical representation of the label-free quantification (LFQ) intensities registered for proteins altered in the serum of COVID-19 PCR + (n:8) and COVID-19 IgG + asymptomatic patients (n:27) compared to COVID-19 negative donors (n:29). Differences were considered significant when p-values < 0.05. *p-value < 0.05, *p-value < 0.01, *p-value < 0.001. C Functional network, obtained with String on-line platform, highlighting the interactions detected between the serum proteins altered in the groups analyzed. Some of the most relevant functions identified for these proteins are represented