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Table 2 Functional classification of differentially expressed proteins in CACs after PCR + serum vs Neg serum incubation

From: The serum of COVID-19 asymptomatic patients up-regulates proteins related to endothelial dysfunction and viral response in circulating angiogenic cells ex-vivo

Functions P-value Z-score Molecules Proteins
Cell movement 2.62E-04 0.602 CAPN2, CD44, FLNA, GLUL, ICAM1, MMP14, PRDX2, RALA, RAP1A, RDX, RTN4, SEPTIN9, SQSTM1, STAB1, TLR2 15
Cell Migration 3.07E-04 0.321 CAPN2, CD44, FLNA, GLUL, ICAM1, MMP14, PRDX2, RALA, RAP1A, RDX, RTN4, SEPTIN9, STAB1, TLR2 14
Viral infection 3.47E-04 0.401 ACSL1, CD44, FLNA, GLUL, HLA-C, ICAM1, MNDA, MYO1F, NCF1, NDRG1, PTGES3, SAMSN1, STAB1, TLR2 14
Apoptosis 1.78E-03 1.037 CD44, DYNLL1, EWSR1, FLNA, H1-0, MNDA, NDRG1, PPP2CA, PRDX2, RAP1A, RDX, RTN4, SQSTM1, TLR2 14
Necrosis 1.42E-02 0.284 CD44, DYNLL1, EWSR1, FLNA, ICAM1, IQGAP2, PPP2CA, PRDX2, RDX, RTN4, SQSTM1, TLR2 12
Cell survival 2.45E-04 0.943 CD44, EIF3A, FLNA, ICAM1, LILRB4, NDRG1, PRDX2, RPS11, SQSTM1, TLR2, XRCC5 11
Vasculogenesis 4.31E-06 1.545 CD44, FLNA, GLUL, ICAM1, MMP14, RAP1A, RDX, RTN4, STAB1, TLR2 10
Infection by RNA virus 1.88E-03 − 0.442 ACSL1, CD44, FLNA, HLA-C, MYO1F, PTGES3, SAMSN1, STAB1, TLR2 9
Cell activation 1.66E-04 0.669 CD44, EIF3A, FLNA, ICAM1, LILRB4, MMP14, PPP2CA, TLR2 8
Endothelial Cell Migration 4.28E-05 0.275 CD44, FLNA, GLUL, ICAM1, MMP14, RTN4, STAB1 7
Leukocytes Cell movement 1.09E-03 0.281 CD44, ICAM1, MMP14, RTN4, STAB1, TLR2 6
Phagocytes Migration 4.25E-05 0.453 CD44, ICAM1, MMP14, RTN4, STAB1 5
ROS production 2.71E-04 0.322 CD44, HVCN1, NCF1, PRDX2, TLR2 5