Fig. 7

Risperidone promotes TNF-α expression to inhibit SATB2 expression in vivo. A, the mRNA expression of TNF-α and SATB2 in femur tissues of mice determined by RT-qPCR. B, Western blot analysis of TNF-α and SATB2 expression in femur tissues of mice. The band intensity was quantified. C, the expression of TNF-α in the serum of mice was evaluated by ELISA. *p < 0.05, compared with mice introduced with lentivirus expressing si-NC. ^#p < 0.05, compared with mice introduced with cRisperidone + lentivirus expressing si-NC. ^&p < 0.05, compared with mice introduced with Risperidone + lentivirus expressing si-TNF-α. The experiments are repeated 3 times n = 6