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Fig. 5 | Molecular Medicine

Fig. 5

From: The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer

Fig. 5

CREB1 differentially regulated MBNL1 under normal and cancer stages. A Western blot analysis for MBNL1 expression was performed with cell lysate from GES-1 and NCI-N87 transfected with CREB1 lentivirus vectors (Left) or siRNA specific to CREB1 (Right). B Correlation between CREB1 and MBNL1 in diagnostic tumor samples (n = 56, r = 0.419, P = 0.01) and normal samples (n = 52, r = 0.153, P = 0.276). C Representative IHC staining of CREB1 and MBNL1 in tumor and normal samples (400 ×). *Means significant P-value < 0.05, NS means no significant, correlation between CREB1 and MBNL1 expression was analyzed by Spearman test

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