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Fig. 2 | Molecular Medicine

Fig. 2

From: α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function

Fig. 2

GTS-21 attenuates intestinal permeability and reduces intestinal bacterial translocation in DSS-induced colitis mice. A The gut mucosal permeability was evaluated by measuring the leakage of fluorescein isothiocyanate (FITC)–dextran from the intestinal pouch. ***p < 0.001. B Bacteria penetrating in DSS-induced colitis was determined by fluorescence in-situ hybridization (FISH) of EUB338 probe (green, EUB338 probe; blue, DAPI nuclear staining). Magnification, ×400. Scale bar, 100 nm

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Molecular Medicine

ISSN: 1528-3658