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Fig. 4 | Molecular Medicine

Fig. 4

From: α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates DSS-induced intestinal colitis by improving intestinal mucosal barrier function

Fig. 4

GTS-21 improves the tight junction (TJ) proteins expressions and distribution in Caco2 monolayers. A Western blot analysis of Caco2 cellular TJ proteins (ZO-1, claudin-1, occludin, JAM-1) expressions level in each group with stimulation of different concentrations of TNF-α for 24 h. B Western blot analysis of Caco2 cellular TJ proteins (ZO-1, claudin-1, occludin, JAM-1) expressions level in different groups. C Representative immunofluorescence of ZO-1 and JAM-1 (red), claudin-1 and occludin (green) in Caco-2 monolayers. (DAPI nuclear staining). Magnification, ×400. Scale bar, 100 nm

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Molecular Medicine

ISSN: 1528-3658