UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis

Table 2 Univariate and multivariate Cox regression analyses of UBE2S

Characteristics	Total (N)	Univariate analysis		Multivariate analysis
Characteristics	Total (N)	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
Grade	181
G1-G2	53
G3	128	5.786 (3.009–11.128)	< 0.001	6.184 (2.862–13.362)	< 0.001
FIGO stage	181
I–II	23
III–IV	158	3.773 (1.535–9.278)	0.004	3.732 (1.154–12.076)	0.028
Lymph node metastasis	181
−	123
+	58	0.677 (0.442–1.037)	0.073
Residual lesion size	181
0	150
2	31	0.489 (0.267–0.894)	0.020	0.541 (0.294–0.995)	0.048
UBE2S expression level	181
High	149
Low	32	0.372 (0.193–0.717)	0.003	2.368 (0.888–6.320)	0.045

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