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Fig. 4 | Molecular Medicine

Fig. 4

From: Hydroxychloroquine induces apoptosis of myeloid-derived suppressor cells via up-regulation of CD81 contributing to alleviate lupus symptoms

Fig. 4

CD81 plays a crucial role in HCQ treatment by increasing the apoptosis of MDSCs. A, B The expression level of CD81 in MDSCs of blood and spleen was determined by FACS (A) and Western blotting (B) (n = 6 mice/group). C The number of MDSCs in blood and spleen was measured by FACs and compared with that of achieved statistically (n = 6 mice/group). D The percentage of Annexin V+ in MDSCs in blood and spleen was determined by FACs (n = 6 mice/group). Data are presented as the mean ± standard error of the mean (SEM). *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001

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Molecular Medicine

ISSN: 1528-3658