Fig. 4

A NFs M1–M7 were prepared from different saRNA template sequences. Cell survival rates after 12, 24, 48, or 72 h were determined using the CCK-8 assay. P > 0.05 vs Ctrl. B–D Relative MiR155HG expression levels at 24 h, 48 h, or 72 h after treatment of HUVECs with NFs M1–M7. E–G Relative miR-155 expression levels at 24 h, 48 h, or 72 h after treatment of HUVECs with NFs M1–M7 (*P < 0.05 vs Ctrl; **P < 0.01 vs Ctrl; ***P < 0.001 vs Ctrl). (H) Relative miR-155 expression in HUVECs treated with M5 for 24 h, 48 h, or 72 h (*P < 0.05 vs Ctrl; **P < 0.01 vs Ctrl; ***P < 0.001 vs Ctrl)