Fig. 5
Adipocyte lipid composition is altered by THRSP silencing. a Significantly altered phospholipid, glycerophospholipid and sphingolipid metabolism genes and their log2 fold-changes (log2 FC; Padj ≤ 0.05). b Log2 FC of lipid class concentrations between ss2 and sirTHRSP (n = 12, two independent experiments). c Log2 FC of hexosyl ceramide (HexCer) species. TG, triglycerides; DG, diglycerides; LPC, lyso-phosphatidylcholines; PE P, phosphatidylethanolamine plasmalogens; HexCer, hexosylceramides; Cer, ceramides; SM, sphingomyelins; PC O, phosphatidylcholine ethers; PC, phosphatidylcholines; PI, phosphatidylinositols; PG, phosphatidylglycerols; PS, phosphatidylserines; PE, phosphatidylethanolamines; LPE, lyso-phosphatidylethanolamines; FC, free cholesterol. Statistical significance is designated as **Padj < 0.01, ***Padj < 0.001, ****Padj < 0.0001