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Fig. 7 | Molecular Medicine

Fig. 7

From: Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages

Fig. 7

The role of the lncARAT/miRNA-329-5p/SOCS2 axis in regulating macrophage function. qRT-PCR (A) and western blot (B and C) analysis of SOCS2 expression in U937 macrophages overexpressing lncARAT in the presence or absence of miRNA-329-5p. qRT-PCR (D) and western blot (E and F) analysis of SOCS2 expression in U937 macrophages treated with silncARAT in the presence or absence of miRNA-329-5p inhibitor. qRT-PCR (G) and western blot (H and I) analysis of IL-10, CD206, and Arg1 expression in U937 macrophages overexpressing lncARAT in the presence or absence of siSOCS2. J–L Western blot and quantitative analysis of p-STAT1 and p-STAT6 levels in U937 macrophages overexpressing lncARAT in the presence or absence of siSOCS2. *p < 0.05. **p < 0.01

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Molecular Medicine

ISSN: 1528-3658