Fig. 1
From: m6A-modified circRNAs: detections, mechanisms, and prospects in cancers
Biogenesis and biological functions of circRNAs. A The biogenesis models of circRNAs include lariat-driven circularization, intron pairing-driven circularization, RBP-driven circularization, intronic lariat, and splicing of pre-tRNA. B Based on the origin of circRNA, it can be divided into four categories, namely EcircRNA, EIciRNA, CiRNA, and TricRNA. C CircRNAs serve four main biological functions, including acting as miRNA sponges, interacting with RBPs, translating into proteins, and regulating gene transcription