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Fig. 6 | Molecular Medicine

Fig. 6

From: Recombinant truncated latency-associated peptide alleviates liver fibrosis in vitro and in vivo via inhibition of TGF-β/Smad pathway

Fig. 6

Detection of the effect of LAP and tLAP on fibrosis-related protein and mRNA expression in C57BL/6 mice. A Detection of the mRNA expression of IL-1β, IL-6, TNF-α, TGF-β, α-SMA, Collagen I, Collagen IV, and Fibronectin in C57BL/6 mice. B Detection of the expression of IL-1β, IL-6, α-SMA, collagen I and Fibronectin in C57BL/6 mice. ***P < 0.001 vs control group; #P < 0.05 vs CCl4 group; ##P < 0.01 vs CCl4 group. ###P < 0.001 vs CCl4 group; P < 0.05, TGF-β1 + tLAP group vs TGF-β1 + LAP group; P < 0.01, TGF-β1 + tLAP group vs TGF-β1 + LAP group

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