Table 6 Expression levels of miRNAs targeting i.a. TYMS mRNA in cancer
From: MALAT1-miRNAs network regulate thymidylate synthase and affect 5FU-based chemotherapy
miRNA | Level†| Cancers‡ | References |
|---|---|---|---|
miR-197-3p | Down | HCT8Fu (5FU resistant) vs HCT8 (parental sensitive) | Wang et al. (2019a) |
| Â | Down | CRC tissues, HCT116, LoVo, HT29, SW480 cell lines | Lu et al. (2018) |
| Â | Down | after treatment with 5FU in HCT116 cell line | Zhou et al. (2010) |
| Â | Down | GC tissues and two cell lines | Han and Liu (2021) |
| Â | Down | GC tissues | Niu et al. (2020) |
| Â | Down | GC tissues | Chen et al. (2019c) |
| Â | Down | GC tissues and four cell lines | Liao et al. (2018) |
| Â | Up | NSCLC tissues and four cell lines (i.a. A549, H460, H1299) | Yang et al. (2019) |
| Â | Up | NSCLC (LUAD) tissues | Chen and Yang (2018) |
| Â | Up | BLCA tissues and four cell lines (i.a. T24) | Jiang et al. (2019b) |
| Â | Up | BLCA tissues and three cell lines (i.a. T24) | Wang et al. (2016a) |
| Â | Up | BRCA tissues and MCF-7, T47D cell lines (ER+ luminal A) | Li et al. (2021d) |
| Â | Up | BRCA 11 cell lines, TNBC vs luminal | Ye et al. (2019) |
| Â | Up | BRCA (TNBC) tissues | Tang et al. (2018) |
| Â | Down | HCC tissues | Bi et al. (2021) |
| Â | Down | HCC tissues and three cell lines | Ni et al. (2019) |
| Â | Up | HCC tissues with metastasis vs non-metastasis | Hu et al. (2018a) |
| Â | Up | HCC cell lines | Dai et al. (2014) |
| Â | Down | CeCa tissues | Gu et al. (2021) |
| Â | Down | CeCa tissues and four cell lines | Hu et al. (2018b) |
| Â | Down | OVCA tissues and four cell lines | Xie et al. (2020) |