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Table 6 Expression levels of miRNAs targeting i.a. TYMS mRNA in cancer

From: MALAT1-miRNAs network regulate thymidylate synthase and affect 5FU-based chemotherapy

miRNA Level Cancers References
miR-197-3p Down HCT8Fu (5FU resistant) vs HCT8 (parental sensitive) Wang et al. (2019a)
  Down CRC tissues, HCT116, LoVo, HT29, SW480 cell lines Lu et al. (2018)
  Down after treatment with 5FU in HCT116 cell line Zhou et al. (2010)
  Down GC tissues and two cell lines Han and Liu (2021)
  Down GC tissues Niu et al. (2020)
  Down GC tissues Chen et al. (2019c)
  Down GC tissues and four cell lines Liao et al. (2018)
  Up NSCLC tissues and four cell lines (i.a. A549, H460, H1299) Yang et al. (2019)
  Up NSCLC (LUAD) tissues Chen and Yang (2018)
  Up BLCA tissues and four cell lines (i.a. T24) Jiang et al. (2019b)
  Up BLCA tissues and three cell lines (i.a. T24) Wang et al. (2016a)
  Up BRCA tissues and MCF-7, T47D cell lines (ER+ luminal A) Li et al. (2021d)
  Up BRCA 11 cell lines, TNBC vs luminal Ye et al. (2019)
  Up BRCA (TNBC) tissues Tang et al. (2018)
  Down HCC tissues Bi et al. (2021)
  Down HCC tissues and three cell lines Ni et al. (2019)
  Up HCC tissues with metastasis vs non-metastasis Hu et al. (2018a)
  Up HCC cell lines Dai et al. (2014)
  Down CeCa tissues Gu et al. (2021)
  Down CeCa tissues and four cell lines Hu et al. (2018b)
  Down OVCA tissues and four cell lines Xie et al. (2020)
  1. ,For description see footnote to Table 2