Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis

Table 1 Cardiac function parameters of the left ventricle

	LVEF	LVFS	LVIDd	LVIDs	LVPWd
	(%)	(%)	(mm)	(mm)	(mm)
Sham	83.10 ± 1.57	46.67 ± 1.58	7.02 ± 0.82	3.75 ± 0.50	1.42 ± 0.18
HF	44.48 ± 3.95^††††	19.41 ± 2.17^††††	9.70 ± 0.67^††††	7.76 ± 0.56^††††	1.63 ± 0.31
HF + F	55.25 ± 3.60****	25.46 ± 2.08****	8.77 ± 0.96*	6.56 ± 0.79****	1.58 ± 0.46
HF + F + BD	44.80 ± 2.24^####	19.59 ± 1.18^####	9.74 ± 0.65^#	7.83 ± 0.49^####	1.73 ± 0.53

LVEF, left ventricular ejection fraction; LVFS, left ventricular systolic percentage; LVIDd, left ventricular end-diastolic internal diameter; LVIDs, left ventricular end-systolic inner diameters; LVPWd, left ventricular posterior wall diastole; ^†P HF group vs sham group; *P HF + F group vs. HF group; ^#P HF + F + BD group vs HF + F group. *^,^#: P<0.05; ^{††††,}****^, ####: P<0.001

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