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Table 2 Parameters of hemodynamics, cardiac structure, and NT-proBNP

From: Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis

 

HW/TL

NT-proBNP

LVSP

LVEDP

LV dP/dtmax

LV dP/dtmin

Ratio

(pg/ml)

(mmHg)

(mmHg)

(mmHg)

(mmHg)

Sham

0.026 ± 0.0007

220.8 ± 15.37

147.8 ± 18.98

5.18 ± 4.35

8138 ± 702.5

− 5753 ± 446.7

HF

0.034 ± 0.0007††††

504.2 ± 78.88††††

108.9 ± 10.17††

19.91 ± 3.80††††

2242 ± 472.5††††

− 2063 ± 429.2††††

HF + F

0.029 ± 0.0013****

344.7 ± 35.04**

131.1 ± 12.61

10.29 ± 1.77***

4226 ± 564.1****

− 3170 ± 807.1*

HF + F + BD

0.033 ± 0.0007####

501.9 ± 103.10##

110.4 ± 19.05

15.92 ± 3.96#

2557 ± 472.8###

− 2102 ± 573.4#

  1. HW/TL, heart weight/tibial length; NT-proBNP, NT-proBNP concentration in serum; LVSP, LV systolic pressure; LVEDP, LV end-diastolic pressure; LV dp/dtmax, LV dp/dtmin, maximal rate of pressure rise and decline (dP/dtmax and dP/dtmin); †P HF group vs sham group; *P HF + F group vs. HF group; #P HF + F + BD group vs HF + F group. *, #: P<0.05; ††, **, ##: P<0.01; ***, ###: P<0.005; ††††, ****, ####: P<0.001 Â