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Table 1 Long COVID-19 outpatient demographics and clinical data

From: Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism

Initial infection variable

Outpatients (n = 23)

Age (yrs), median (IQR)

61.0 (19.0)

Male sex, no. (%)

13 (56.5)

Diagnostic test: PCR, serology, no. (%)

23 (100.0)

Vaccination status at infection, no. (%)

2 (8.7)

Hospitalization, no. (%)

 

 Ward

7 (30.4)

 ICU

1 (4.3)

Comorbidities, no. (%)

 

 Diabetes

6 (26.1)

 Hypertension

8 (34.8)

 Coronary artery/heart disease

2 (8.7)

 Chronic/congestive heart failure

0 (0.0)

 Chronic kidney disease

0 (0.0)

 Cancer

1 (4.3)

 COPD

0 (0.0)

 Asthma

4 (17.4)

Presenting symptoms at infection, no. (%)

 

 Fever

16 (69.6)

 Cough

18 (78.3)

 Anosmia/ageusia

14 (60.9)

 Pharyngitis

9 (39.1)

 Headache

14 (60.9)

 Confusion/memory

2 (8.7)

 Myalgias

13 (56.5)

 Dyspnea

16 (69.6)

 Chest pain

8 (34.8)

 Nausea/vomiting/diarrhea

12 (52.2)

Interventions at infection, no. (%)

 

 Steroids

7 (30.4)

 Remdesivir

1 (4.3)

 Tocilizumab

1 (4.3)

Long-COVID clinic variables

 

 Follow up, days from infection onset, median (IQR)

98.5 (47.5)

Lingering symptoms at follow up, no. (%)

 

 Respiratory

16 (69.6)

 Cardiovascular

6 (26.1)

 Neurology

9 (39.1)

 Musculoskeletal

1 (4.3)

 Gastro-Intestinal

3 (13.0)

 Psychiatric

1 (4.3)

 Cutaneous

0 (0.0)

 Balance

0 (0.0)

 Chest pain

4 (17.4)

 Concentration

1 (4.3)

 Cough

2 (8.7)

 Dyspnea

16 (69.6)

 Fatigue

11 (47.8)

 Headache

2 (8.7)

 Low mood

1 (4.3)

 Anxiety

1 (4.3)

 Memory

7 (30.4)

 Nausea

1 (4.3)

 Palpitations

1 (4.3)

 Paresthesia

 1 (4.3)

 Smell/taste

2 (8.7)

 Word finding

2 (8.7)

 Non-specific

11 (47.8)

Laboratories at follow up, median (IQR)

 

 White blood cell count

7.1 (2.0)

 Neutrophils

4.5 (1.6)

 Lymphocytes

2.0 (0.6)

 Hemoglobin

140.0 (22.5)

 Platelets

230.0 (59.5)

 C-Reactive Protein (CRP)

1.8 (3.5)

 Ferritin

86.5 (133.8)

 Lactate dehydrogenase (LDH)

201.0 (37.0)

 Alanine aminotransferase (ALT)

20.0 (10.5)

Interventions at follow up, no. (%)

 

 Pulmicort

1 (4.3)

 Anticoagulant

1 (4.3)

 Symbicort

10 (43.5)

 Ventolin

3 (13.0)

 Lasix

1 (4.3)

 Nasal spray

2 (8.7)

 Oxygen

2 (8.7)

 Physiotherapy

5 (21.7)

 None

8 (34.8)