Fig. 1From: Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patientsCharacterization of plasma sEVs. sEVs were freshly isolated from plasma of HNC, NED patients and HD by size-exclusion chromatography and characterized for their morphology, particle concentration and protein content. A Representative TEM images of sEVs from HNC, NED patients and HD are shown (magnification = 25.000x, scale = 100 nm). B Size distribution, concentration and median diameter of the particles were detected using NTA. C NTA particle concentration of HNC, NED patients and HD were visualized by scatter plots. D Comparison of total protein content in 1 mL of isolated sEVs measured by BCA protein assays. E Western blots were performed using 10 μg protein and the presence of typical vesicle proteins CD9, CD63 and TSG101 and the absence of contaminating proteins (Grp94, ApoA1) were shown. P values below 0.05 were considered as significant (*p < 0.05)Back to article page