Fig. 6From: Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patientsProliferation and apoptosis of HUVECs in the presence of plasma sEVs. HUVECs and plasma sEVs from HNC patients, NED and HDs were co-incubated for 24 h. Proliferation (MTS assay) and apoptosis induction (Caspase3/7) of HUVECs was detected and visualized by scatter plots. The percentage changes compared to the PBS control (dotted line) after stimulation for 24 h is shown. The plots of the A MTS Assay and B Caspase-Glo 3/7 assay show the inhibition of proliferation and apoptosis induction by sEVs in relation to the disease activity and tumor stage of the HNC patients. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001Back to article page