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Fig. 6 | Molecular Medicine

Fig. 6

From: Plasma-derived small extracellular vesicles unleash the angiogenic potential in head and neck cancer patients

Fig. 6

Proliferation and apoptosis of HUVECs in the presence of plasma sEVs. HUVECs and plasma sEVs from HNC patients, NED and HDs were co-incubated for 24 h. Proliferation (MTS assay) and apoptosis induction (Caspase3/7) of HUVECs was detected and visualized by scatter plots. The percentage changes compared to the PBS control (dotted line) after stimulation for 24 h is shown. The plots of the A MTS Assay and B Caspase-Glo 3/7 assay show the inhibition of proliferation and apoptosis induction by sEVs in relation to the disease activity and tumor stage of the HNC patients. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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