Table 1 S100 proteins in cardiovascular diseases

S100A1

Acute myocardial ischemia (Kiewitz et al. 2000; Fan et al. 2019)

Heart failure (Pleger et al. 2007, 2008, 2011; Desjardins et al. 2009; Belmonte et al. 2011; Soltani et al. 2021; Brinks et al. 2011; Ehlermann et al. 2000)

Pulmonary hypertension (Teichert-Kuliszewska et al. 2015)

Myocardial ischemia/reperfusion injury (Jungi et al. 2018)

Acute coronary syndrome (Fan et al. 2019; Li et al. 2018)

Acute aortic dissection (Han et al. 2021)

S100A2

Heart failure (Wang et al. 2014b)

S100A4

Acute myocardial infarction (Doroudgar et al. 2016; Gong et al. 2015)

Unstable angina (Yang et al. 2019)

Heart failure (Tamaki et al. 2013)

Myocardial hypertrophy (Sato et al. 2017; Qi et al. 2016; Qian et al. 2018a)

Viral myocarditis (Wang et al. 2019)

Atherosclerosis and restenosis of coronary artery lesions (Brisset et al. 2007; Choe et al. 2017; Nagata et al. 2020; Sakic et al. 2022)

S100A5

Atherosclerosis (Awad et al. 2018)

S100A6

Acute myocardial infarction (Cai et al. 2011; Mofid et al. 2017)

Early adverse left ventricular remodeling after infarction (Tsoporis et al. 2014)

S100A7

Atherosclerosis (Awad et al. 2018)

S100A8/A9

Myocardial infarction (Sreejit et al. 2020; Nagareddy et al. 2020)

Myocardial ischemia/reperfusion injury (Li et al. 2019)

Heart failure (Volz et al. 2012; Ma et al. 2012; Wei et al. 2015)

Autoimmune myocarditis (Otsuka et al. 2009)

Inflammatory cardiomyopathy (Müller et al. 2017)

Takayasu arteritis (Goel et al. 2018)

Acute coronary syndrome (Sakuma et al. 2017; Altwegg et al. 2007; Santilli et al. 2014; Ionita et al. 2010)

Atherosclerosis (Croce et al. 2009; Eue et al. 2000; Kraakman et al. 2017; Miyamoto et al. 2008; Farris et al. 2011; Hirata et al. 2012; Ionita et al. 2009; McCormick et al. 2005; Maiseyeu et al. 2012)

Coronary artery disease (Jonasson et al. 2017; Xia et al. 2016)

Arterial thrombosis (Chen et al. 2018)

Very late stent thrombosis (Wang et al. 2020a)

Intracranial aneurysm (Korte et al. 2019, 2020)

Abdominal aortic aneurysm (Liu et al. 2019)

Aneurysmal subarachnoid hemorrhage (Wang et al. 2020b)

Cardiac sarcoidosis (Terasaki et al. 2007)

S100A11

Infective endocarditis (Snipsøyr et al. 2016)

S100A12

Atherosclerosis (Goyette et al. 2009; Scicali et al. 2019; Farokhzadian et al. 2019)

Familial hypercholesterolemia (Scicali et al. 2019)

Left ventricular hypertrophy (Yan et al. 2014)

Aortic valve calcification (Yan et al. 2014)

S100B

Ventricular remodeling after myocardial infarction (Tsoporis et al. 2005b; Mohammadzadeh et al. 2013)

Cerebral infarction (Garzelli et al. 2020)

Atrial fibrillation (Zhang et al. 2013; Scherschel et al. 2019)

Acute coronary syndrome (Cai et al. 2011)

Dilated cardiomyopathy (Mazzini et al. 2007)

Heart failure (Li et al. 2011; Chen et al. 2020)

Myocardial infarction (Tsoporis et al. 2010)

Atherosclerosis (Wu et al. 2019)

Cerebral ischemia/reperfusion injury (Yuan et al. 2019)

Aortic aneurysm (Roberts et al. 2021)

Cardiac arrest (Deye et al. 2020)