Figure 6
From: Angiotensin II-Mediated Endothelial Dysfunction: Role of Poly(ADP-ribose) Polymerase Activation
The absence of PARP-1 prevents the AII-induced endothelial dysfunction. Acetylcholine-induced endothelium-dependent relaxations are shown. Each point of the curve represents mean ± SEM of 6 experiments in vascular rings. *P < 0.05 denotes significant loss of endothelium-dependent relaxations in the AII-treated wild-type mice, when compared with the response in vehicle-treated wild-type mice.