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Table 1 Porphobilinogen deaminase (PBGD) activities in tissues from PBGD-deficient and control mice

From: Biochemical Characterization of Porphobilinogen Deaminase-Deficient Mice During Phenobarbital Induction of Heme Synthesis and the Effect of Enzyme Replacement

 

PBGD activity (pkat/g protein) (mean ± SD)

Tissue

PBGD-deficient mice (n = 12)

Control mice (n = 11)

% of control

Blood cells

36.7 ± 19.7

126 ± 72.6

29

Lung

35.4 ± 3.3

85 ± 14.7

42

Kidney

29.9 ± 6.2

91.5 ± 6.4

33

Heart

29.9 ± 2.2

78.6 ± 7.2

38

Brain

18.1 ± 3.6

64.7 ± 7.5

28

Muscle

13.4 ± 3.6

39.2 ± 1.6

34

Spleen

142 ± 195

644 ± 430

22