Table 2 Down-regulation of specific gene expression in human vascular endothelial cells treated with interleukin-4

Adhesion molecules

ITGA2

NM_002203

−3.6

<0.001

Integrin α2

Cytokines, chemokines, and receptors

IL8

NM_000584

−5.6

<0.001

Interleukin-8

IL7R

NM_002185

−3.4

0.005

Interleukin-7 receptor

CXCL2

M57731

−2.2

0.001

Chemokine (C-X-C motif) ligand 2

Growth factors and receptors

GAS1

NM_002048

−14.0

0.007

Growth arrest-specific 1

NDRG4

AV724216

−2.1

0.011

NDRG family member 4

EGFR

AW157070

−2.1

0.006

Epidermal growth factor receptor

PDGFB

NM_002608

−2.0

0.029

Platelet-derived growth factor β polypeptide

Signal transduction

KIT

NM_000222

−9.0

<0.001

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

ITPKB

NM_002221

−2.6

0.001

Inositol 1,4,5-triphophate 3-kinase B

RAB11B

AL575337

−2.2

0.016

RAB11B, member RAS oncogene family

TNS

AL046979

−2.0

0.036

Tensin

Transcription factors

KLF15

NM_014079

−2.7

0.004

Kruppel-like factor 15

SNAPC4

AK023513

−2.2

0.002

Small nuclear RNA activating complex, polypeptide 4, 190 kDa

NPAS2

AW000928

−2.1

<0.001

Neuronal PAS domain protein 2

HOXB6

NM_018952

−2.0

0.011

Homeo box B6

Others

GJA4

NM_002060

−4.8

0.006

Gap junction protein (connexin 37)

HIP14

AF161412

−2.9

0.019

Huntingtin interacting protein 14

KCNN2

NM_021614

−2.8

<0.001

Potassium intermediate/small conductance calcium-activated channel N2

AMN

NM_030943

−2.6

0.029

Amnionless homolog

NFNG

AI760053

−2.6

0.023

Manic fringe homolog

CLTB

X81637

−2.5

0.032

Clathrin light chain b gene

CHST2

NM_004267

−2.2

<0.001

Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2

FLJ12800

NM_022903

−2.2

0.030

Hypothetical protein FLJ12800

CLDN18

BE551219

−2.2

0.046

Claudin 18

RASGRP3

NM_015376

−2.1

0.003

RAS guanine releasing protein 3

CYP2A6

NM_000762

−2.1

<0.001

Cytochrome P450 2A6

TRPV5

NM_019841

−2.1

0.008

Trasient receptor potential cation channel, subfamily V, member 5

CAV3

NM_001234

−2.0

0.021

Caveolin 3

BPAG1

BG253119

−2.0

0.031

Bullous pemphigoid antigen 1

WIZ

AL390184

−2.0

0.009

Widely interspaced zinc finger motifs

Unknown

CHI3L1

AJ251847

−4.3

0.005

CHI3L1 gene for cartilage glycoprotein-39

R29124_1

BF110434

−3.3

0.004

Hypothetical protein R29124_1

FLJ11983

AK022045

−2.9

0.004

FLJ11983 fis, clone HEMBA1001337

PRO1598

NM_018503

−2.7

0.022

Hypothetical protein PRO1598

FLJ10002

AK000864

−2.6

0.007

FLJ10002 fis, clone HEMBA1000046

FLJ23497

NM_025089

−2.6

0.044

Hypothetical protein FLJ23497

KIAA0795

NM_025010

−2.5

0.013

KIAA0795 protein

HL14

M14087

−2.4

0.049

HL14 gene encoding β-galactoside-binding lectin

FLJ20378

AI734156

−2.2

0.033

Hypothetical protein FLJ20378

LOC92346

AL035295

− 2.0

0.040

PAC 106H8, similar to Dynamin