Figure 2
From: Oral Adsorbent AST-120 Decreases Serum Levels of AGEs in Patients with Chronic Renal Failure
Effects of patient serum on atherosclerosis-related gene expression in HUVECs. HUVECs were treated with patient serum before or after AST-120 treatment for 12 h, and RAGE, VCAM, and MCP-1 mRNA levels were determined. Upper panel shows representative RT-PCR bands of these genes. Each lower panel shows the quantitative representation of each gene induction. Data were normalized by the intensity of β-actin mRNA-derived signals and related to the value of the control. *P < 0.05 compared with the value before AST-120 treatment.