Figure 1
From: Intracellular Evaluation of ER Targeting Elucidates a Mild Form of Inherited Coagulation Deficiency
Computational analysis of FVII prepeptide sequence. (A) Amino acid sequence of the FVII prepeptide and prediction of the secondary structure. Amino acid substitutions are indicated. The hydrophobic core is shown (box). The vertical bold line represents the signal peptidase cleavage site. h, helix; c, random coil; e, extended strand; t, β turn. (B) Prediction of the signal peptide score with different computational programs.