Table 2 Characteristics of SNPs used in linkage analysis
From: Real-Time PCR and Linkage Studies to Identify Carriers Presenting HPRT Deleted Gene
SNP | Restriction enzyme | Distance from exon 1 of HPRT | Average allele frequency | Average heterozygosity |
|---|---|---|---|---|
rs6638241 | — | ∼5 kb; in intron 1 | C: 0.809 | 0.219 ±0.248 |
T: 0.191 | ||||
rs6638240 | — | ∼2 kb; in intron 1 | C: 0.220 | 0.219 ±0.248 |
T: 0.780 | ||||
rs1468266 | Msel | ∼22 kb; in intron 3 | A: 0.309 | 0.406 ±0.195 |
T: 0.691 | ||||
rs6634993 | Haell | ∼35 kb; in intron 6 | G: 0.780 | 0.219 ±0.248 |
A: 0.220 |