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Figure 15 | Molecular Medicine

Figure 15

From: The Histone Deacetylase Inhibitor ITF2357 Reduces Production of Pro-Inflammatory Cytokines In Vitro and Systemic Inflammation In Vivo

Figure 15

Effect of ITF2357 on ConA-induced hepatitis in BALB/C mice. BALB/C mice (10 per group) received either a single oral dose (100 µL) of 5 mg/kg of ITF2357 or an equivalent volume of water (Controls). After 30 min, both groups received an intravenous injection of ConA (200 µg per mouse). Mean ± SEM serum ALT are shown after 24 h. **P < 0.01 versus ConA with water vehicle.

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