Figure 4

ADCC of hCAb against human colorectal cancer cell lines. Each data point represents the mean± SD specific lysis (%) measured in 3 independent experiments. Percent specific lysis was calculated as 100% × (sample release — spontaneous release)/(maximal release — spontaneous release); where maximal ⁵¹Cr release was determined by adding 5% SDS to target cells, and spontaneous release was measured in the absence of sensitizing antibody and effector cells. *Results were considered significant (P < 0.05, versus control groups).