Figure 5
Effect of VEGF165 on keratinocyte migration. Incubation with VEGF165 significantly increases keratinocyte migration, and this induction is partially abrogated by pre-treatment with VEGFR-2 neutralizing antibody. Data are expressed as mean values ± SD for the total number of cells observed in 5 randomly selected fields from 3 separate wells. **P ≤ 0.01; ***P < 0.001, significant differences between VEGF-treated and untreated cells. ###P < 0.001, significant difference between VEGF-treated cells and cells treated with both VEGF and VEGFR-2 neutralizing antibody.