Figure 2

Incorporation of (³H)glucosamine into total and individual GAG classes secreted by N-SP (A) and CLP-SP (B) fibroblasts treated (black bars) or not (white bars) with RA. The results are shown as mean ± SD of 4 separate experiments for each of the 4 patients; each experiment was performed in quadruplicate. HA indicates hyaluronan; HS, heparan sulphate; CS, chondroitin-4 and -6 sulphate; DS, dermatan sulphate. The statistical analysis was performed with ANOVA. CLP-SP fibroblasts vs. N-SP fibroblasts: §F test significant at 99%; treated N-SP and CLP-SP fibroblasts vs. individual GAG classes of untreated group: *Ftest significant at 99%, **F test significant at 95%.