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Figure 5 | Molecular Medicine

Figure 5

From: Differential Reactions of Microglia to Brain Metastasis of Lung Cancer

Figure 5

The percentage of annexin+/PI− cells in each treatment obtained by manual counting from micrographs taken under a confocal fluorescent microscope. In 24- and 36-h treatment groups, an increasing number of apoptotic cells parallels the increasing concentration of the LPS-BVCM, indicating that microglia-induced lung cancer cell apoptosis is initially dose and time dependent. The data are presented as means and standard deviations. Statistically significant differences (P < 0.05) are found between the following pairs of groups: 1) At 12 h, no difference between various groups; 2) at 24 h, 0%, 10%, 25%, 50%, or 75% group vs. 100% group and 0%, 10%, or 25% group vs. 75% group; 3) at 36 h, 0%, 10%, 25%, 50%, or 75% group vs. 100% group; 0%, 10%, or 25% group vs. 75% group; and 0%, 10%, or 25% vs. 50% group; 4) at 48 h, 0%, 10%, 25%, 50%, or 75% group vs. 100% group; 0%, 10%, 25% or 50% group vs. 75% group; and 0%, 10%, or 25% vs. 50% group.

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