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Figure 4 | Molecular Medicine

Figure 4

From: CD151 Gene Delivery Activates PI3K/Akt Pathway and Promotes Neovascularization after Myocardial Infarction in Rats

Figure 4

Expression of PI3K, phosphor-Akt, total Akt, phosphor-eNOS, total eNOS, and VEGF after CD151 gene delivery. Four weeks after coronary artery ligation, samples were taken from the same regions as the ischemic heart. (A) Western blot of PI3K, phosphorAkt, total Akt, phosphor-eNOS, and total eNOS in hearts of different groups. (B, C, D) Quantitative analysis of phosphor-Akt, phosphor-eNOS, total Akt, total eNOS. The mean density of PI3K (B), phosphor-Akt and total Akt (C), and phosphor-eNOS and total eNOS (D) in sham-operated mice was defined as 100%. (E, F) Quantitative analysis of VEGF. The mean density of VEGF in sham-operated mice was defined as 100%. Data are means ± SEM. *P > 0.05 vs. AMI + saline, AMI + rAAV-GFP. #P < 0. 05 vs. sham.

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Molecular Medicine

ISSN: 1528-3658