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Table 1 Hemodynamic variables and physiological parameters

From: CD151 Gene Delivery Activates PI3K/Akt Pathway and Promotes Neovascularization after Myocardial Infarction in Rats

Parameter

Sham

AMI + saline

AMI + rAAV-GFP

AMI + rAAV-CD151

n

8

6

6

7

BW, g

341.38 ± 11.61

344.83 ± 11.77

353.67 ± 19.44

343 ± 17.18

LVW, mg

721.3 ± 22.90

755 ± 15.17

746.7 ± 45.46

717.14 ± 22.15

HW, mg

853.25 ± 39.88

1075 ± 94.18

1086.67 ± 127.23

942.57 ± 56.21

LVW/BW, mg/g

2.11 ± 0.07

2.14 ± 0.05

2.13 ±0.11

2.09 ± 0.07

HW/BW, mg/g

2.50 ± 0.11

3.08 ± 0.29*

3.07 ± 0.25*

2.75 ± 0.08†

LVEDP, mmHg

3.51 ± 0.61

23.27 ± 2.42*

23.3 ± 3.26*

4.89 ± 8.81†

LVESP, mmHg

135.66 ± 2.00

113.5 ± 3.54*

115.20 ±2.26*

126.11 ± 2.64†

+dp/dtmax, mmHg/s

7400.75 ± 129.27

3522.33 ± 307.66*

3713 ± 195.53*

6073.29 ±407.96†

−dp/dtmax, mmHg/s

4417.13 ± 142.75

3764.83 ± 99.91*

3710.83 ± 170.10*

3992.29 ± 120.60†

  1. At 4 weeks after coronary artery ligation, hemodynamic variables were monitored using a catheter tip manometer advanced from the right carotid artery via the aortic arch into the left ventricle at the end of the experiment. Data represent means ± SEM. BW, body weight; HW, heart weight; LVW, left ventricular weight; LVEDP, left ventricle end-diastolic pressure; LVESP, left ventricle end-systolic pressure; ±dp/dtmax, maximal rate of increase and decline in left ventricular pressure. *P< 0. 05 vs. sham; †P< 0.05 vs. sham, AMI + saline, and AMI + rAAV-GFP.