Figure 2
From: Nonhematopoietic Erythropoietin Derivatives Prevent Motoneuron Degeneration In Vitro and In Vivo
Effects of Epo against toxicity induced by kainate. Viability of SMI 32-positive motoneurons in mixed neuron/glia cultures after 48-h incubation with kainate (5 µM). When present, EPO (2.5 pmol/mL) was added simultaneously with the glutamate agonists (B), 3 days before treatment (C), or both (A). Data represent mean ± SD of 12 replications. *P < 0.05, **P < 0.01, different from controls; °P < 0.05, different from kainate + EPO.