Figure 3

Fibroblasts grown from distinct wound locations have different response to wounding and different migration capacity in the wound scratch essay in vitro. Fibroblasts from Location B migrate similar to normal whereas fibroblasts from the location A have diminished migration capacity. (A) Actual experiment is shown. Full lines indicate initial wound area; dotted lines demarcate migrating front of cells. (B) Histograms indicate the average coverage of scratch wounds widths in % relative to baseline wound width at the 0, 4, 8, and 24 h.