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Figure 1 | Molecular Medicine

Figure 1

From: Imbalance in Seminal Fluid MIF Indicates Male Infertility

Figure 1

(A) Structure of dopachrome methyl ester, a chromogenic substrate used in enzymatic assays of MIF, and its tautomerized colorless product. (B) Relationship between seminal fluid MIF concentrations and the dopachrome decolorizing rate (tautomerase activity) (n = 18, r2 = 0.88); Seminal fluid exhibited dopachrome tautomerase activity. (C) MIF tautomerase activity in seminal fluids obtained from normozoospermic subjects (controls, n = 27) and patients with abnormal sperm parameters (n = 68, P< 0.001).

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