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Table 2 263 transcripts differentially expressed In AS cells as compared with control samples. Transcripts are ordered by their Apert-to-control ratios (Log 2).

From: Apert p.Ser252Trp Mutation in FGFR2 Alters Osteogenic Potential and Gene Expression of Cranial Periosteal Cells

Gene (Official Symbol)

Gene name

Accession number

SNRa

P value

Apert-to-control Ratio (Log2)

x-fold down-regulated in Apert

DKFZp434B 1231 b

eEF1A2 binding protein

NM_178275.3

−0.86

0.010

−2.66

6.31

TNNT1 c

troponin T type 1 (skeletal, slow)

F36108.1

−0.662

0.017

−2.45

5.46

TNXB b

tenascin XB

NM_032470.2

−0.769

0.015

−2.32

4.98

CYHR1 b

cysteine/histidine-rich 1

AB007965.1

−1.013

0.010

−2.21

4.62

RTN4RL 1 b

reticulon 4 receptor-like 1

AL834409.1

−0.812

0.023

−1.83

3.57

CCRL1

chemokine (C-C motif) receptor-like 1

NM_016557.2

−0.65

0.035

−1.77

3.42

NISC_np07a06y1 NICHD_HS_Ut1

NISC_np07a06yl NICHD_

CB215524.1 HS_Ut1 cDNA clone IMAGE:5936938 5′

−0.422

0.047

−1.76

3.39

PCNXL2 b

pecanex-like 2 (Drosophila)

NM_014801.2

−0.773

0.023

−1.75

3.36

CFB

complement factor B

NM_001710.3

−0.678

0.027

−1.74

3.34

DDIT4 b

DNA-damage-inducible transcript 4

NM_019058.1

−0.564

0.022

−1.71

3.28

RARRES3 b

retinoic acid receptor responder (tazarotene induced) 3

NM_004585.2

−0.773

0.022

−1.64

3.12

ZC3H12A

zinc finger CCCH-type containing 12A

NM_025079.1

−0.499

0.047

−1.62

3.08

PIK3C2B c

phosphoinositide-3-kinase, class 2, β polypeptide

NM_002646.2

−0.903

0.004

−1.54

2.91

TP53I11

tumor protein p53 inducible protein ll

BC045666.1

−0.702

0.026

−1.48

2.79

GBP2

guanylate binding protein 2, interferon-inducible

NM_004120.3

−0.689

0.031

−1.43

2.69

ChGn c

chondroitin betal,4 N-acetylgalactosaminyltransferase

NM_018371.3

−0.819

0.015

−1.42

2.68

ZNF385 b

zinc finger protein 385

NM_015481.1

−0.955

0.011

−1.38

2.61

UI-E-CQ1-aew-i-06-0-UIr1 UI-E-CQ1

UI-E-CQ1-aew-i-06-0-UIr1 UI-E-CQ1 cDNA clone UI-E-CQ1-aew-i-06-0-UI 5′

BM695626.1

−0.661

0.042

−1.37

2.59

PDGFRA

platelet-derived growth factor receptor, α polypeptide

NM_006206.2

−0.653

0.045

−1.34

2.53

LRRC17 b

leucine rich repeat containing 17

NM_005824.1

−0.643

0.039

−1.25

2.38

yr27d04r1

yr27d04r1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:206503 5′

H59349.1

−0.708

0.039

−1.25

2.38

MGC:71335 b

cDNA clone MGC:71335 IMAGE:6088873

BC067086.1

−0.825

0.009

−1.25

2.37

FLJ43880 c

cDNA FLJ43880 fis, clone TESTI4009022

AK125868.1

−0.796

0.017

−1.24

2.36

ADAM33

ADAM metallopeptidase domain 33

NM_153202.1

−0.709

0.027

−1.22

2.33

RC6-HT0840-150800-022-D11 HT0840

RC6-HT0840-150800-022-D11 HT0840 Homo sapiens cDNA

BE719128.1

−0.678

0.031

−1.22

2.33

FXYD1

FXYD domain containing ion transport regulator 1 (phospholemman)

NM_021902.2

−0.578

0.044

−1.20

2.29

MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

NM_005360.2

−0.568

0.044

−1.19

2.29

ABI3BP c

ABI gene family, member 3 (NESH) binding protein

NM_015429.2

−0.705

0.012

−1.17

2.26

UI-E-DW1-ahc-b-11-0-UIr1 UI-E-DW1 c

UI-E-DW1-ahc-b-11-0-UIr1 UI-E-DW1 cDNA clone UI-E-DW1-ahc-b-11-0-UI 5′

BM712072.1

−0.854

0.008

−1.14

2.21

MTSS1 b

metastasis suppressor 1

NM_014751.2

−0.731

0.009

−1.14

2.20

CLDN15 b

claudin 15

NM_014343.1

−0.714

0.022

−1.13

2.19

GANAB

glucosidase, alpha; neutral AB

NM_198334.1

−0.719

0.020

−1.13

2.19

C1QTNF1 c

C1q and tumor necrosis factor related protein 1

NM_030968.2

−0.672

0.017

−1.13

2.18

ATF3

activating transcription factor 3

NM_004024.2

−0.619

0.049

−1.10

2.14

C17orf58 c

chromosome 17 open reading frame 58

NM_181655.1

−0.813

0.007

−1.10

2.14

P2RY6 c

pyrimidinergic receptor P2Y, G-protein coupled, 6

NM_004154.3

−0.814

0.021

−1.08

2.12

ADAM8 c

a disintegrin and metalloproteinase domain 8

NM_001109.1

−0.628

0.044

−1.06

2.08

PNRC1

proline-rich nuclear receptor coactivator 1

NM_006813.1

−0.902

0.008

−1.05

2.07

FLJ23438 b

cDNA: FLJ23438 fis, clone HRC13275

AK027091.1

−0.738

0.016

−1.04

2.06

BTN3A3 c

butyrophilin, subfamily 3, member A3

NM_197974.1

−0.833

0.009

−1.03

2.05

UI-H-EU0-azp-a-24-0-UUs1 NCI_CGAP_Car1 b

UI-H-EU0-azp-a-24-0-UIs1 NCI_CGAP_Car1 cDNA clone IMAGE: 5851679 3′

BQ181011.1

−0.716

0.009

−1.01

2.01

CREB5 b

cAMP responsive element binding protein 5

NM_004904.1

−0.9

0.010

−1.00

2.00

HLA-G

HLA-G histocompatibility antigen, class I, G

NM_002127.3

−0.721

0.028

−0.99

1.99

MATN2

matrilin 2

NM_030583.1

−0.743

0.027

−0.96

1.95

HHLA2

HERV-H LTR-associating 2

NM_007072.2

−0.488

0.024

−0.95

1.93

HLA-F

major histocompatibility complex, class I, F

NM_018950.1

−0.619

0.039

−0.95

1.93

TXNIP

thioredoxin interacting protein

NM_006472.1

−0.604

0.034

−0.94

1.92

KLF11

Kruppel-like factor 11

NM_003597.4

−0.493

0.039

−0.92

1.89

ARID5A

AT rich interactive domain 5A (MRF1-like)

NM_006673.2

−0.526

0.042

−0.92

1.89

PERP

PERP, TP53 apoptosis effector

NM_022121.2

−0.602

0.042

−0.92

1.89

HHLA1

HERV-H LTR-associating 1

NM_005712.1

−0.661

0.031

−0.92

1.89

GYPC b

glycophorin C (Gerbich blood group)

NM_002101.3

−0.578

0.046

−0.91

1.88

NUCB1

nucleobindin 1

NM_006184.3

−0.618

0.026

−0.89

1.86

LGALS3BP b

lectin, galactoside-binding, soluble, 3 binding protein

NM_005567.2

−0.784

0.014

−0.89

1.85

FLJ20099 b

cDNA FLJ20099 fis, clone COL04544

AK000106.1

−0.711

0.023

−0.89

1.85

TMEM142C b

transmembrane protein 142C

NM_152288.1

−0.803

0.011

−0.87

1.83

ATXN2L

ataxin 2-like

NM_007245.2

−0.596

0.046

−0.87

1.83

PAQR6 b

progestin and adipoQ receptor family member VI

NM_024897.2

−0.63

0.040

−0.87

1.83

SPTBN1

spectrin, beta, non-erythrocytic 1 (SPTBN1)

NM_003128.1

−0.62

0.049

−0.87

1.83

MGC15875 b

hypothetical protein MGC15875 (MGC15875)

NM_032921.1

−0.894

0.013

−0.86

1.81

MAPK8IP1

mitogen-activated protein kinase 8 interacting protein 1

NM_005456.2

−0.642

0.037

−0.86

1.81

ANKZF1

ankyrin repeat and zinc finger domain containing 1

NM_018089.1

−0.673

0.036

−0.85

1.81

CCBE1

collagen and calcium binding EGF domains 1

NM_133459.1

−0.602

0.034

−0.85

1.81

DKFZp779O 1626

mRNA; cDNA DKFZp779O1626 (from clone DKFZp779O1626)

BX648538.1

−0.676

0.027

−0.83

1.78

CA12

carbonic anhydrase XII

AK000158.1

−0.612

0.040

−0.83

1.78

NFIL3 b

nuclear factor, interleukin 3 regulated

NM_005384.1

−0.803

0.012

−0.83

1.77

IFITM3

interferon induced transmembrane protein 3 (1-8U)

NM_021034.1

−0.604

0.033

−0.83

1.77

SLC27A1

solute carrier family 27 (fatty acid transporter), member 1

NM_198580.1

−0.621

0.047

−0.81

1.75

LAMP1

lysosomal-associated membrane protein 1

NM_005561.2

−0.648

0.037

−0.80

1.74

BCL3

B-cell CLL/lymphoma 3

NM_005178.2

−0.671

0.039

−0.79

1.73

R15896ya 47b07.r1

R15896 ya47b07.r1 Soares infant brain 1NIB cDNA clone IMAGE:53125 5′ similar to SP:S37009 S37009 TRANSPOSASE — ALMOND;

R15896.1

−0.645

0.037

−0.79

1.73

ZFP64 b

zinc finger protein 64 homolog (mouse)

NM_018197.2

−0.795

0.017

−0.78

1.72

SWAP-70 b

SWAP-70 protein

AB014540.1

−0.708

0.028

−0.77

1.71

P2RX4

purinergic receptor P2X, ligand-gated ion channel, 4

NM_002560.2

−0.69

0.032

−0.77

1.71

BMP1

bone morphogenetic protein 1 (BMP1)

NM_006129.2

−0.598

0.048

−0.76

1.69

SLC25A37

solute carrier family 25, member 37

NM_016612.1

−0.607

0.039

−0.75

1.68

NUB1 b

negative regulator of ubiquitin-like proteins 1

NM_016118.3

−0.68

0.011

−0.75

1.68

ACADS

acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain

NM_000017.1

−0.669

0.046

−0.74

1.67

RELB

v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian)

NM_006509.2

−0.682

0.033

−0.74

1.67

PPARA b

peroxisome proliferative activated receptor, α

NM_032644.1

−0.753

0.009

−0.74

1.67

ELL3 b

elongation factor RNA polymerase II-like 3

NM_025165.1

−0.791

0.006

−0.74

1.67

BCL6 c

B-cell CLL/lymphoma 6 (zinc finger protein 51)

NM_001706.2

−0.819

0.013

−0.74

1.67

PYGL c

phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI)

NM_002863.2

−0.804

0.016

−0.74

1.67

cDNA clone fs01a035′

fs01a03y1 Human Lens cDNA (Normalized): fs cDNA clone fs01a03 5′

CD673362.1

−0.615

0.030

−0.73

1.66

602156641F1 NH_MGC _83

602156641F1 NIH_MGC_83 cDNA clone IMAGE:4297258 5′

BF681513.1

−0.597

0.037

−0.73

1.66

CSNK2A1

casein kinase 2, α 1 polypeptide

NM_177560.2

−0.693

0.030

−0.73

1.66

KIAA0082

KIAA0082

NM_015050.1

−0.945

0.010

−0.72

1.65

UI-E-DW0-agh-c-03-0-UIr1 UI-E-DW0 c

UI-E-DW0-agh-c-03-0-UIr1 UI-E-DW0 cDNA clone UI-E-DW0-agh-c-03-0-UI 5′

BM706230.1

−0.714

0.024

−0.72

1.65

CNTNAP1

contactin associated protein 1

NM_003632.1

−0.628

0.041

−0.72

1.64

SYNGR1 b

synaptogyrin 1

NM_004711.3

−0.635

0.043

−0.71

1.64

ING4

inhibitor of growth family, member 4

NM_198287.1

−0.586

0.044

−0.69

1.62

RBM5 b

RNA binding motif protein 5

NM_005778.1

−0.71

0.024

−0.69

1.61

FLJ34274

cDNA FLJ34274 fis, clone FEBRA2003327

AK091593.1

−0.618

0.044

−0.68

1.60

FAM113A b

family with sequence similarity 113, member A

NM_022760.3

−0.796

0.015

−0.68

1.60

MAP3K6

mitogen-activated protein kinase kinase kinase 6

NM_004672.3

−0.584

0.041

−0.67

1.59

FLJ14360

hypothetical protein FLJ14360

NM_032775.2

−0.638

0.030

−0.67

1.59

B4GALT7 b

xylosylprotein β 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

NM_007255.1

−0.76

0.026

−0.66

1.57

CASP7 b

caspase 7, apoptosis-related cysteine peptidase

NM_001227.2

−0.637

0.023

−0.65

1.57

IXL b

intersex-like (Drosophila)

AL137304.1

−0.662

0.031

−0.65

1.57

RHBDF2

rhomboid-like protein 6

NM_024599.2

−0.636

0.030

−0.65

1.57

UCN

urocortin

NM_003353.2

−0.625

0.044

−0.65

1.57

FLRT2

fibronectin leucine rich transmembrane protein 2

NM_013231.3

−0.595

0.042

−0.64

1.56

FLJ45129

cDNA FLJ45129 fis, clone BRAWH3037394

AK127072.1

−0.582

0.048

−0.63

1.55

LKAP c

limkain b1

NM_014647.1

−0.693

0.012

−0.63

1.55

yj34b04r1 b

yj34b04r1 Soares placenta Nb2HP cDNA clone IMAGE:150607 5′

H02050.1

−0.722

0.017

−0.62

1.54

HECA b

headcase homolog (Drosophila)

NM_016217.1

−0.629

0.047

−0.62

1.54

BMP1 b

bone morphogenetic protein 1

NM_006129.2

−0.763

0.024

−0.62

1.54

601194047F1 NIH_MGC_7

601194047F1 NIH_MGC_7 cDNA clone IMAGE:3537995 5′

BE264943.1

−0.699

0.048

−0.62

1.54

TNIP2 b

TNFAIP3 interacting protein 2

NM_024309.2

−0.95

0.008

−0.62

1.54

ZNF688

zinc finger protein 688

NM_145271.2

−0.669

0.026

−0.61

1.53

MITF

microphthalmia-associated transcription factor

NM_006722.1

−0.62

0.042

−0.60

1.51

FLJ45204 b

cDNA FLJ45204 fis, clone BRCAN2009168

AK127147.1

−0.807

0.010

−0.60

1.51

UBXD7 c

UBX domain containing 7

AB018337.1

−0.811

0.007

−0.58

1.50

C16orf48 b

hypothetical protein DKFZp434A1319 (DKFZP434A1319)

NM_032140.1

−0.714

0.015

−0.58

1.50

ZFHX4

zinc finger homeodomain 4

NM_024721.2

−0.643

0.030

−0.58

1.49

yo60a08r1

yo60a08r1 Soares breast 3NbHBst cDNA clone IMAGE:182294 5′ similar to contains Alu repetitive element; contains LTR9 repetitive element

H41942.1

−0.692

0.031

−0.58

1.49

ZNF44

zinc finger protein 44

BC032246.1

−0.614

0.032

−0.57

1.49

SETD5

SET domain containing 5

AB051544.1

−0.6

0.031

−0.57

1.48

RNF103

ring finger protein 103

NM_005667.2

−0.648

0.031

−0.57

1.48

TP53INP1

tumor protein p53 inducible nuclear protein 1

NM_033285.2

−0.642

0.028

−0.55

1.47

yr35b01r1

yr35b01r1 Soares fetal liver spleen 1NFLS

H59642.1

−0.631

0.038

−0.55

1.46

Soares fetal liver spleen 1NFLS b

cDNA clone IMAGE:207241 5′

     

BBS1

Bardet-Biedl syndrome 1

NM_024649.4

−0.616

0.047

−0.54

1.46

FLJ43900

cDNA FLJ43900 fis, clone TESTI4009973

AK125888.1

−0.669

0.043

−0.54

1.45

ITM2B b

integral membrane protein 2B

NM_021999.2

−0.681

0.028

−0.54

1.45

PDE6G b

phosphodiesterase 6G, cGMP-specific, rod, gamma

NM_002602.1

−0.87

0.003

−0.53

1.44

FKBP4

FK506 binding protein 4, 59kDa

NM_002014.2

−0.697

0.023

−0.53

1.44

CHKB

choline kinase β (CHKB)

NM_005198.3

−0.593

0.039

−0.52

1.43

FLJ11946 b

cDNA FLJ11946 fis, clone HEMBB1000709

AK022008.1

−0.922

0.005

−0.50

1.42

wi65f08× 1 NCI_CGAP_Kid12

wi65f08×1 NCI_CGAP_Kid12 cDNA clone IMAGE:2398215 3′

AI763182.1

−0.621

0.044

−0.50

1.42

NSMAF c

neutral sphingomyelinase (N-SMase) activation associated factor

NM_003580.2

-0.789

0.015

−0.50

1.41

SIX5 b

sine oculis homeobox homolog 5 (Drosophila)

NM_175875.3

−0.75

0.017

−0.49

1.40

64B2 Human retina cDNA Tsp509I-cleaved sublibrary b

64B2 Human retina cDNA Tsp509I-cleaved sublibrary Homo sapiens cDNA not directional

W22248.1

−0.684

0.022

−0.48

1.39

XPC

xeroderma pigmentosum, complementation group C

NM_004628.2

−0.644

0.041

−0.48

1.39

603040523F1 NIH_MGC_115

603040523F1 NIH_MGC_115 cDNA clone IMAGE:5181509 5′

BI824163.1

−0.708

0.030

−0.48

1.39

DKFZp686 K2137

mRNA; cDNA DKFZp686K2137 (from clone DKFZp686K2137)

AL833529.1

−0.626

0.037

−0.47

1.38

SRRM2

serine/arginine repetitive matrix 2

NM_016333.2

−0.632

0.042

−0.45

1.36

SH3GLB2

SH3-domain GRB2-like endophilin B2

NM_020145.2

−0.662

0.037

−0.45

1.36

yd89d12r1 Soares fetal liver spleen 1NFLS

yd89d12r1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:115415 5′

T87528.1

−0.592

0.050

−0.43

1.35

cDNAclone IMAGE: 3636922

cDNA clone IMAGE:3636922

BC062348.1

−0.598

0.035

−0.43

1.34

PTPRA

protein tyrosine phosphatase, receptor type, A

NM_002836.2

−0.624

0.042

−0.41

1.33

C20orf111

chromosome 20 open reading frame 111

NM_016470.6

−0.632

0.043

−0.41

1.33

MGAT1 b

mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase

NM_002406.2

−0.799

0.019

−0.40

1.32

ZDHHC3 b

zinc finger, DHHC domain containing 3

NM_016598.1

−0.634

0.040

−0.32

1.25

cDNA DKFZp 313K127 b

mRNA; cDNA DKFZp313K127 (from clone DKFZp313K127)

AL833316.1

−0.74

0.024

−0.31

1.24

GANAB

glucosidase, alpha; neutral AB

NM_198334.1

−0.676

0.034

−0.31 x-fold up-regulated in Apert

1.24

NUBP2

nucleotide binding protein 2 (MinD homolog, E coli)

NM_012225.1

0.66

0.030

0.23

1.17

AGENCOURT_8454944 NIH_MGC_113

AGENCOURT_8454944 NIH_MGC_113 cDNA clone IMAGE:6278846 5′

BU899205.1

0.587

0.046

0.28

1.22

ATP5G1

ATP synthase, H + transporting, mitochondrial F0 complex, subunit C1 (subunit 9)

NM_005175.1

0.618

0.042

0.28

1.22

AGENCOURT_8073800 NIH_MGC_110 b

AGENCOURT_8073800 NIH_MGC_110 cDNA clone IMAGE:6083397 5′

BU147450.1

0.678

0.020

0.32

1.25

CIB1 b

calcium and integrin binding 1 (calmyrin)

NM_006384.2

0.665

0.035

0.32

1.25

ARL3

ADP-ribosylation factor-like 3

NM_004311.2

0.633

0.033

0.34

1.27

PSMA2

proteasome (prosome, macropain) subunit, α type, 2

NM_002787.3

0.648

0.039

0.36

1.28

MAGED2 b

melanoma antigen, family D, 2

NM_014599.4

0.599

0.030

0.36

1.28

CUTA

cutA divalent cation tolerance homolog (E. coli)

NM_015921.1

0.603

0.044

0.37

1.29

CSNK1D

casein kinase 1, delta

NM_001893.3

0.614

0.042

0.37

1.29

MTCH2

mitochondrial carrier homolog 2 (C elegans) (MTCH2), nuclear gene encoding mitochondrial protein

NM_014342.2

0.576

0.045

0.38

1.30

yp83b01s1 Soares fetal liver spleen 1NFLS

yp83b01s1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:193993 3′

H51256.1

0.597

0.049

0.38

1.30

MAPRE1

microtubule-associated protein, RP/EB family, member 1

NM_012325.1

0.613

0.045

0.38

1.30

SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

NM_003072.2

0.658

0.034

0.39

1.31

PLA2G12A

phospholipase A2, group XIIA

NM_030821.3

0.668

0.044

0.39

1.31

METTL2B b

methyltransferase like 2

NM_018396.1

0.753

0.019

0.40

1.32

EEF1B2 c

eukaryotic translation elongation factor 1 β 2

NM_001959.2

0.879

0.011

0.40

1.32

GABPB2

GA binding protein transcription factor, β subunit 2

NM_002041.2

0.664

0.027

0.40

1.32

ZNF414 b

zinc finger protein 414

NM_032370.1

0.742

0.029

0.41

1.32

ADCY2 b

adenylate cyclase 2 (brain)

NM_020546.1

0.665

0.028

0.41

1.33

CASP8AP2

CASP8 associated protein 2

NM_012115.2

0.621

0.049

0.41

1.33

TIMP3 c

TIMP metallopeptidase inhibitor 3

BG104808.1

0.966

0.006

0.42

1.34

EIF4A1

eukaryotic translation initiation factor 4A

NM_001416.1

0.585

0.038

0.44

1.35

MUS81 b

MUS81 endonuclease homolog (S. cerevisiae)

NM_025128.3

0.662

0.024

0.44

1.35

CCDC72

coiled-coil domain containing 72

NM_015933.1

0.694

0.030

0.44

1.36

SNRPD1

small nuclear ribonucleoprotein D1 polypeptide 16kDa

NM_006938.2

0.619

0.044

0.44

1.36

DTYMK

deoxythymidylate kinase

NM_012145.2

0.64

0.037

0.44

1.36

STX2 b

syntaxin 2

NM_194356.1

0.745

0.019

0.44

1.36

AARSD1 b

alanyl-tRNA synthetase domain containing 1

NM_025267.2

0.786

0.019

0.45

1.37

CREB3 b

cAMP responsive element binding protein 3

NM_006368.4

0.743

0.023

0.46

1.38

COX4NB

neighbor of COX4 (NOC4)

NM_006067.3

0.593

0.030

0.47

1.38

PDZK6

PDZ domain containing 6

NM_015693.2

0.63

0.038

0.47

1.39

UBE2N

ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)

NM_003348.3

0.584

0.037

0.48

1.39

PPIH

peptidyl prolyl isomerase H

NM_006347.3

0.676

0.025

0.48

1.40

SIKE

suppressor of IKK epsilon

NM_025073.1

0.584

0.048

0.50

1.41

TK1

thymidine kinase 1, soluble

NM_003258.1

0.685

0.028

0.50

1.41

PAFAH1B3

platelet-activating factor acetylhydrolase, isoform Ib, γ subunit 29kDa

NM_002573.2

0.651

0.037

0.51

1.42

SFRS7 b

splicing factor, arginine/serine-rich 7, 35kDa

NM_006276.36

0.705

0.028

0.52

1.44

PSMC5

proteasome (prosome, macropain) 26S subunit, ATPase, 5

NM_002805.4

0.624

0.043

0.53

1.44

yr11c06r1 Soares fetal liver spleen 1NFLS b

yr11c06r1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:204970 5′

H57392.1

0.742

0.015

0.53

1.44

C15orf29 b

chromosome 15 open reading frame 29

NM_024713.1

0.793

0.011

0.53

1.44

GFOD2 c

glucose-fructose oxidoreductase domain containing 2

NM_030819.2

0.745

0.019

0.53

1.45

HN1

hematological and neurological expressed 1

NM_001002032.1

0.683

0.045

0.54

1.46

DKFZp451H129

mRNA; cDNA DKFZp451H129 (from clone DKFZp451H129)

AL833295.1

0.649

0.035

0.54

1.46

CKLF b

chemokine-like factor

NM_016951.2

0.726

0.021

0.55

1.46

OBFC1

oligonucleotide/oligosaccharide-binding fold containing 1

NM_024928.3

0.688

0.027

0.55

1.46

VAMP4 b

vesicle-associated membrane protein 4, transcript variant 1

NM_201994.1

0.744

0.010

0.55

1.46

RRM1

ribonucleotide reductase M1 polypeptide

NM_001033.2

0.612

0.045

0.55

1.46

PSME4 b

proteasome (prosome, macropain) activator subunit 4

NM_014614.1

0.736

0.022

0.56

1.47

PLK3

polo-like kinase 3 (Drosophila)

NM_004073.2

0.642

0.036

0.57

1.48

MRPL35 b

mitochondrial ribosomal protein L35

NM_016622.2

0.706

0.014

0.57

1.49

DLAT b

dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)

NM_001931.2

0.707

0.019

0.58

1.49

HIP2 b

huntingtin interacting protein 2

NM_005339.3

0.723

0.017

0.58

1.49

C20orf7

chromosome 20 open reading frame 7

NM_199052.1

0.615

0.041

0.59

1.50

UFD1L b

ubiquitin fusion degradation 1 like (yeast)

NM_005659.3

0.616

0.023

0.59

1.51

POP5

processing of precursor 5, ribonuclease P/MRP subunit (S cerevisiae) (POP5)

NM_015918.3

0.623

0.041

0.59

1.51

SLC35B3

solute carrier family 35, member B3

NM_015948.2

0.628

0.037

0.60

1.51

CDKN3

cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)

NM_005192.2

0.613

0.044

0.60

1.52

LZIC b

leucine zipper and CTNNBIP1 domain containing

NM_032368.3

0.766

0.019

0.60

1.52

LETM1

leucine zipper-EF-hand containing transmembrane protein 1

NM_012318.1

0.589

0.049

0.60

1.52

RNASEH2A b

ribonuclease H2, subunit A

NM_006397.2

0.869

0.011

0.60

1.52

NEDD1

neural precursor cell expressed, developmentally downregulated 1

NM_152905.2

0.643

0.041

0.62

1.53

CEP78

centrosomal protein 78kDa

AW962072.1

0.672

0.028

0.63

1.54

UI-H-BI0-aah-e-06-0-UIs1 NCI_CGAP_Sub1

UI-H-BI0-aah-e-06-0-UIs1 NCI_CGAP_Sub1 cDNA clone IMAGE:2709227 3′

AW014009.1

0.597

0.037

0.63

1.55

CKAP2

cytoskeleton associated protein 2

NM_018204.2

0.644

0.037

0.66

1.58

ACTR3B b

ARP3 actin-related protein 3 homolog B (yeast)

NM_020445.1

0.765

0.016

0.67

1.59

ELAVL1

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

NM_001419.2

0.635

0.041

0.67

1.59

POLR3K b

polymerase (RNA) III (DNA directed) polypeptide K

NM_016310.2

0.802

0.013

0.69

1.61

PI4KII b

phosphatidylinositol 4-kinase type II

NM_018425.2

0.77

0.014

0.69

1.62

TMEM107 b

transmembrane protein 107

NM_183065.1

0.739

0.022

0.70

1.62

BCAP29

B-cell receptor-associated protein 29

NM_018844.1

0.644

0.040

0.70

1.63

PRPS1L1 b

phosphoribosyl pyrophosphate synthetase 1-like 1

NM_175886.2

0.728

0.022

0.71

1.63

MTFMT b

mitochondrial methionyl-tRNA formyltransferase

NM_139242.2

0.866

0.008

0.72

1.64

DDX49

DEAD (Asp-Glu-Ala-Asp) box polypeptide 49

NM_019070.3

0.61

0.046

0.73

1.66

RAD1 b

RAD1 homolog (S. pombe)

NM_002853.2

0.71

0.018

0.73

1.66

CMTM5

CKLF-like MARVEL transmembrane domain containing 5

NM_138460.2

0.721

0.019

0.74

1.67

NEK6 b

NIMA (never in mitosis gene a)-related kinase 6

NM_014397.3

0.715

0.017

0.74

1.67

K-EST0149992 L3SNU475 b

K-EST0149992 L3SNU475 cDNA clone L3SNU475-29-H12 5′

CB108944.1

0.657

0.015

0.75

1.68

yx15f01s1 Soares melanocyte 2NbHM b

yx15f01s1 Soares melanocyte 2NbHM cDNA clone IMAGE:261817 3′

H99198.1

0.766

0.015

0.76

1.70

EXOSC9 b

exosome component 9

NM_005033.1

0.721

0.021

0.76

1.70

UI-E-CI0-aah-e-03-0-UIr1 UI-E-CI0

UI-E-CI0-aah-e-03-0-UIr1 UI-E-CI0 cDNA clone UI-E-CI0-aah-e-03-0-UI 5′

BM690376.1

0.659

0.031

0.79

1.73

PTS

6-pyruvoyltetrahydropterin synthase

NM_000317.1

0.597

0.047

0.79

1.73

C14orf143

chromosome 14 open reading frame 143

NM_145231.1

0.629

0.047

0.79

1.73

UBE2T

HSPC150 protein similar to ubiquitin-conjugating enzyme

NM_014176.1

0.664

0.029

0.83

1.77

SAE1

SUMO-1 activating enzyme subunit 1

NM_005500.1

0.62

0.049

0.83

1.78

AURKB

aurora kinase B

NM_004217.1

0.692

0.031

0.84

1.79

ARSJ

arylsulfatase family, member J

AK027201.1

0.708

0.028

0.85

1.80

RRM2 b

ribonucleotide reductase M2 polypeptide

NM_001034.1

0.781

0.019

0.86

1.81

BCL7A

B-cell CLL/lymphoma 7A

NM_020993.2

0.652

0.034

0.86

1.82

IVNS1ABP

influenza virus NS1A binding protein

NM_006469.2

0.66

0.035

0.87

1.82

NCAPG

non-SMC condensin I complex, subunit G

NM_022346.2

0.689

0.028

0.87

1.83

CENPM c

centromere protein M

NM_024053.2

0.693

0.006

0.87

1.83

C5orf13

chromosome 5 open reading frame 13

NM_004772.1

0.626

0.042

0.89

1.85

MCM4

MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)

NM_182746.1

0.65

0.030

0.90

1.87

FLJ43294

cDNA FLJ43294 fis, clone MESTC1000042

AK125284.1

0.527

0.049

0.93

1.90

PTPDC1 b

protein tyrosine phosphatase domain containing 1

NM_152422.3

0.725

0.027

0.95

1.93

LOC90624

hypothetical protein LOC90624

NM_181705.1

0.642

0.026

0.95

1.94

SPAG5 b

sperm associated antigen 5

NM_006461.2

0.876

0.007

0.98

1.97

CTPS

CTP synthase

NM_001905.1

0.496

0.046

0.98

1.98

zu70f09r1 Soares_testis_NHT

zu70f09r1 Soares_testis_NHT cDNA clone IMAGE:743369 5′

AA400694.1

0.578

0.039

0.99

1.98

MND1

meiotic nuclear divisions 1 homolog (S. cerevisiae)

NM_032117.2

0.674

0.034

1.00

2.00

KIAA0101

KIAA0101 gene product

NM_014736.3

0.58

0.050

1.02

2.03

ZNF738 c

zinc finger protein 738

BC034499.1

1.07

0.003

1.03

2.04

EHD4 c

EH-domain containing 4

NM_139265.2

0.725

0.001

1.04

2.06

MNS1 b

meiosis-specific nuclear structural 1

NM_018365.1

0.832

0.013

1.06

2.08

ARHGAP11A

similar to human GTPase-activating protein

NM_014783.2

0.7

0.027

1.08

2.12

CENPN c

centromere protein N

NM_018455.3

1.142

0.001

1.10

2.14

STMN1 b

stathmin 1/oncoprotein 18

NM_203401.1

0.969

0.006

1.11

2.16

DUSP2 b

dual specificity phosphatase 2

NM_004418.2

0.953

0.004

1.17

2.25

SPBC25 b

spindle pole body component 25 homolog (S. cerevisiae)

NM_020675.3

0.892

0.010

1.18

2.27

HIST1H4C

histone 1, H4c

NM_003542.3

0.682

0.033

1.22

2.32

TCF19

transcription factor 19 (SC1)

BC033086.1

0.631

0.041

1.23

2.34

CIP29

cytokine induced protein 29 kDa

NM_033082.1

0.65

0.040

1.24

2.36

FLJ39342 b

cDNA FLJ39342 fis, clone OCBBF2018873

AK096661.1

0.776

0.017

1.32

2.50

FLJ23131

cDNA: FLJ23131 fis, clone LNG08502

AK026784.1

0.645

0.039

1.61

3.05

zv03f03r1 Soares_NhHMPu_S1

zv03f03r1 Soares_NhHMPu_S1 cDNA clone IMAGE:752573 5′

AA419568.1

0.718

0.041

1.74

3.34

CNN1

calponin 1, basic, smooth muscle

NM_001299.3

0.808

0.022

2.09

4.24

HAPLN1 c

hyaluronan and proteoglycan link protein 1

NM_001884.2

1.003

0.005

3.00

7.99

  1. aSNR stands for “signal to noise ratio”.
  2. bThe 120 genes identified as differentially expressed in at least 50% of the “leave-one-out” datasets.
  3. cThe 25 genes identified as differentially expressed in 100% of the “leave-one-out” datasets.