Figure 3

Photomicrographs of the jejunal tissue stained by the hematoxylin and eosin in sham-operated animals, vehicle-treated I/R animals, and I/R animals treated with EPO five minutes before ischemia and at the onset of reperfusion. (A) Sham: Histological features of normal jejunal tissue were observed, (B) I/R: The villi are denuded to the level of the lamina propria and dilated capillaries, (C) EPO + I/R: The villi are preserved (D) I + EPO + R: Erosion of the surface epithelium while the architecture of the villi are preserved. Sham; intestinal I/R was not induced, I/R; intestinal I/R, EPO + I/R; rHuEPO administered five minutes before ischemia, I + EPO + R; rHuEPO administered onset of reperfusion (40×).