Cellular, secreted and total GAG production from control (C), sporadic (SAD) and familial (FAD) Alzheimer’s disease fibroblasts and FGF2 effects (+). The values were the mean ± SD of three independent experiments each performed in quintuplicate for n=10 subjects for group. Data were analyzed by ANOVA. Differences vs. respective control; *F-test significant at 99%. Differences vs. respective untreated group; §F-test significant at 99%; §§F-test significant at 95%; ns = not significant.