Figure 2From: Cellular Zinc and Redox Buffering Capacity of Metallothionein/Thionein in Health and DiseaseDrugs change the availability of “free” zinc by several mechanisms. Zinc chelation, induction of TR or generation of TR by reduction of T0 decrease zinc (left). Oxidation or other covalent modification of thiols and compounds that serve as carriers of zinc into the cell increase zinc (right).Back to article page