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Table 2 Summary of LIV-1 Family Expression Response to Treatments or Antihormone Resistance

From: The Emerging Role of the LIV-1 Subfamily of Zinc Transporters in Breast Cancer

Cells ZIP4 ZIP5 LIV-1 HKE4 ZIP8 ZIP10 ZIP12 ZIP13 ZIP14
MCF-7 + E2 ND Up Up Down     Up
MCF-7 + TAM ND Down
MCF-7 + FAS ND Down Down
Tamoxifen-resistant cells ND Up
Fulvestrant-resistant cells ND Up Up
  1. ND, not determined; —, no change.