Figure 5
From: Zinc Inhibits Astrocyte Glutamate Uptake by Activation of Poly(ADP-ribose) Polymerase-1
Zn2+ did not acutely cause cell membrane disruption. Astrocyte membrane integrity was evaluated by measuring the lactate dehydrogenase (LDH) retained in the cultures at serial time points after 30 min incubation with Zn2+. Data points are means of four independent experiments (n = 4), each with measurements from two culture wells. *P < 0.05 versus immediately (zero hours) after zinc removal.