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Table 2 Immune and Biochemical Parameters of Studied Subjectsa

From: The +838 C/G MT2A Polymorphism, Metals, and the Inflammatory/Immune Response in Carotid Artery Stenosis in Elderly People

Parameters

Elderly controls (n = 218)

CS patients (n = 288)

MCP-1 (pg/mL)

87 ±31

93 ± 32b

RANTES (pg/mL)

9249 ± 6064

11094 ± 8450c

IL-6 (pg/mL)

21.1 ± 11

22 ± 14

IL-8 (pg/mL)

7.1 ± 3.9

7.6 ± 4.1

TNF-α (pg/mL)

84 ± 35

83 ± 35

MT (MFI)

20.2 ± 12.7

23.7 ± 15.2c

NK activity (L.U. 20/107)

35.1 ± 5.1

20.5 ± 12.6c

CD56+ (%)

17.8 ± 6.3

17.3 ± 6.0

Zn plasma levels (uM)

12.0 ± 2.1

11.1 ± 2.5c

Cu plasma levels (uM)

18.0 ± 3.5

17.3 ± 4.1b

Mg plasma levels (uM)

1110 ± 540

788 ± 208c

Fe plasma levels (uM)

18.1 ± 6.7

18.9 ± 7.1

Zn (µmol/L RBC)

131 ± 36

122 ± 35c *

Cu (µmol/L RBC)

8.7 ± 1.9

8.5 ± 2.0

Mg (µmol/L RBC)

1451 ± 776

1481 ± 670

Fe (µmol/L RBC)

8477 ± 2834

9056 ± 3335b

Zn availability (MFI/MFImin)

1.35 ± 0.12

1.33 ± 0.10b

  1. aResults are expressed as mean ± SD. MFI = mean fluorescence intensity; L.U. = Lytic Unit.
  2. bP < 0.05 compared with age-matched controls.
  3. cP< 0.01 compared with age-matched controls.