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Table 4 −209 A/G MT2A Genotypic and Allelic Frequencies in CS1 and CS2 Patients and Elderly Controlsa

From: The +838 C/G MT2A Polymorphism, Metals, and the Inflammatory/Immune Response in Carotid Artery Stenosis in Elderly People

 

Elderly controls (n = 218)

CS1 patients (without cerebrovascular episodes) (n = 188)

CS2 patients (n = 100)

 

n

Frequency

n

Frequency

n

Frequency

Genotypes

      

AA (G−)

154

0.71

137

0.73

75

0.75

AG (G +)

56

0.26

48

0.25

24

0.24

GG(G+)

8

0.03

3

0.02

1

0.01

Total

218

 

188

 

100

 

Alleles

      

A allele

364

0.83

322

0.87

174

0.87

G allele

72

0.17

71

0.13

25

0.13

Total

436

 

376

 

200

 
  1. aAll populations were in Hardy Weinberg equilibrium (P> 0.05). No differences of AA genotype distribution of −209 A/G MT2A polymorphism were observed among CS1 patients, CS2 patients, and elderly controls, by using Χ2 test.
  2. A Allele frequencies were similar among CS1 and CS2 patients and elderly controls (OR = 1.179, P= .43, 95% CI = 0.8038–1.731 and OR = 0.9209, P= .2, 95% CI = 0.8066–1.051, respectively) as determined by Fisher exact test using the approximation of Woolf.