| Elderly controls (n = 218) | CS1 patients (without cerebrovascular episodes) (n = 188) | CS2 patients (n = 100) |
---|
 | n | Frequency | n | Frequency | n | Frequency |
---|
Genotypes
| Â | Â | Â | Â | Â | Â |
AA (G−) | 154 | 0.71 | 137 | 0.73 | 75 | 0.75 |
AG (G +) | 56 | 0.26 | 48 | 0.25 | 24 | 0.24 |
GG(G+)
| 8 | 0.03 | 3 | 0.02 | 1 | 0.01 |
Total | 218 | Â | 188 | Â | 100 | Â |
Alleles | Â | Â | Â | Â | Â | Â |
A allele | 364 | 0.83 | 322 | 0.87 | 174 | 0.87 |
G allele | 72 | 0.17 | 71 | 0.13 | 25 | 0.13 |
Total | 436 | Â | 376 | Â | 200 | Â |
- aAll populations were in Hardy Weinberg equilibrium (P> 0.05). No differences of AA genotype distribution of −209 A/G MT2A polymorphism were observed among CS1 patients, CS2 patients, and elderly controls, by using Χ2 test.
- A Allele frequencies were similar among CS1 and CS2 patients and elderly controls (OR = 1.179, P= .43, 95% CI = 0.8038–1.731 and OR = 0.9209, P= .2, 95% CI = 0.8066–1.051, respectively) as determined by Fisher exact test using the approximation of Woolf.