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Table 5 Biochemical and Immune Parameters in Relation to +838 C/G MT2A Genotype in CS Patients

From: The +838 C/G MT2A Polymorphism, Metals, and the Inflammatory/Immune Response in Carotid Artery Stenosis in Elderly People

 

C− genotype N = 197

C + genotype N = 91

Platelet count (×103/mL)

231 ± 45b

211 ± 56

Fibrinogen (mg/dL)

385 ± 79c

360 ± 88

MCP-1 (pg/mL)

99 ± 35d

86 ± 28

RANTES (pg/mL)

10913 ± 7010

11284 ± 9892

IL-6 (pg/mL)

22.6 ± 12.7

21.5 ± 12.5

IL-8 (pg/mL)

7.9 ± 4.1

7.3 ±4.0

TNF-α (pg/mL)

82 ± 33

83 ± 38

MT (MFI)

25 ± 16.1

22 ± 14.2

NK activity (L.U. 20/107)

15.9 ± 9.5d

25.3 ± 15.6

CD56 + (%)

15.1 ± 5.8d

19.5 ±6.2

Zn plasma levels (µM)

10.8 ± 2.6

11.4 ± 2.3e

Cu plasma levels (µM)

16.9 ± 4.6

17.6 ±3.8

Mg plasma levels (µM)

756 ± 237c

820 ± 175

Fe plasma levels (µM)

19.9 ± 8.4c

17.9 ±5.8

Zn (µmol/L RBC)

114 ±40d

130 ± 31

Cu (µmol/L RBC)

8.2 ±1.8f

8.9 ± 2.1

Mg (µmol/L RBC)

1325 ± 662d

1635 ± 680

Fe (µmol/L RBC)

9046 ± 4828

9071 ± 1822

Zn availability (MFI/MFImin)

1.31 ± 0.09d

1.36 ± 0.11

  1. aResults are expressed as mean ± SD. MFI= mean fluorescence intensity; L.U. = Lytic Unit.
  2. bP< 0.005; cP< 0.05; dP< 0.001; eP= .06; fP< 0.001; compared with C + genotypes.