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Table 5 Biochemical and Immune Parameters in Relation to +838 C/G MT2A Genotype in CS Patients

From: The +838 C/G MT2A Polymorphism, Metals, and the Inflammatory/Immune Response in Carotid Artery Stenosis in Elderly People

  C− genotype N = 197 C + genotype N = 91
Platelet count (×103/mL) 231 ± 45b 211 ± 56
Fibrinogen (mg/dL) 385 ± 79c 360 ± 88
MCP-1 (pg/mL) 99 ± 35d 86 ± 28
RANTES (pg/mL) 10913 ± 7010 11284 ± 9892
IL-6 (pg/mL) 22.6 ± 12.7 21.5 ± 12.5
IL-8 (pg/mL) 7.9 ± 4.1 7.3 ±4.0
TNF-α (pg/mL) 82 ± 33 83 ± 38
MT (MFI) 25 ± 16.1 22 ± 14.2
NK activity (L.U. 20/107) 15.9 ± 9.5d 25.3 ± 15.6
CD56 + (%) 15.1 ± 5.8d 19.5 ±6.2
Zn plasma levels (µM) 10.8 ± 2.6 11.4 ± 2.3e
Cu plasma levels (µM) 16.9 ± 4.6 17.6 ±3.8
Mg plasma levels (µM) 756 ± 237c 820 ± 175
Fe plasma levels (µM) 19.9 ± 8.4c 17.9 ±5.8
Zn (µmol/L RBC) 114 ±40d 130 ± 31
Cu (µmol/L RBC) 8.2 ±1.8f 8.9 ± 2.1
Mg (µmol/L RBC) 1325 ± 662d 1635 ± 680
Fe (µmol/L RBC) 9046 ± 4828 9071 ± 1822
Zn availability (MFI/MFImin) 1.31 ± 0.09d 1.36 ± 0.11
  1. aResults are expressed as mean ± SD. MFI= mean fluorescence intensity; L.U. = Lytic Unit.
  2. bP< 0.005; cP< 0.05; dP< 0.001; eP= .06; fP< 0.001; compared with C + genotypes.