Skip to main content
Figure 1 | Molecular Medicine

Figure 1

From: Selective Suppression of NF-kBp65 in Hepatitis Virus-Infected Pregnant Women Manifesting Severe Liver Damage and High Mortality

Figure 1

Gel shift analysis using nuclear extracts from PBMC proteins of different subjects with 32P-labeled oligonucleotide probe harboring an NF-kB consensus sequence. Very low NF-kB binding activity was observed in the healthy pregnant women (lane a), a moderate level of binding activity was observed in disease control (pregnant women with AVH) (lanes b and c), while a very high binding activity was observed in the hepatitis virus infected FHF patients, both nonpregnant (lane d) and pregnant (lane e and f). The positions of the specific retarded bands are indicated. The squares mark the unspecific complexes. The extent of binding activity as revealed by densitometry analysis is indicated below each lane.

Back to article page